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© Quarterly Homœopathic Digest, Vol. XXX1I, 1 - 4, 2015. Private Circulation only.
8. Homœopathic treatment of premenstrual syndrome:
a case series
DANNO Karine, COLAS Aurélie et al.
(HOM. 102, 1/2013)
Objective: Observational, prospective study to describe
the homœopathic management of premenstrual
syndrome (PMS) by a group of French physicians.
Method: Women with PMS for > 3 months were
prescribed individualized homœopathic treatment. The
intensity of 10 clinical symptoms of PMS was scored
individually at inclusion and at a 3-6 month follow-up
visit: absent = 0, mild = 1, moderate = 2, severe = 3.
Total symptom score (range: 0-30) was calculated and
compared for each patient at inclusion and at follow-up
as: none, mild, moderate, severe, very severe.
Results: Twenty-three women were prescribed
homœopathic treatment only (mean age: 39.7 years).
Folliculinum (87%) was the most frequently prescribed
homœopathic medicine followed by Lachesis mutus
(52.2%). The most common PMS symptoms (moderate
or severe) at inclusion were: irritability, aggression and
tension (87%), mastodynia (78.2%) and weight gain and
abdominal bloating (73.9%); and the most common
symptoms at follow-up were: irritability, aggression and
tension (39.1%), weight gain and abdominal bloating
(26.1%) and mastodynia (17.4%). Mean global score
for symptom intensity was 13.7 at inclusion and 6.3 at
follow-up. The mean decrease in score (7.4) was
statistically significant (p <0.0001). twenty-one women
reported that their QoL also improved significantly
(91.3%; p < 0.0001).
Conclusions: Homœopathic treatment was well
tolerated and seemed to have a positive impact on PMS
symptoms. Folliculinum was the most frequent
homœopathic medicine prescribed. There appears to be
scope for a properly designed, randomized, placebo-
controlled trial to investigate the efficacy of individual
homœopathic medicines in PMS. [We have been
treating tens and tens of women with PMS successfully
with single homœopathic remedies = KSS]
9. Testing the nanoparticle-allostatic ccross-
adaptation-sensitization model for homœopathic
remedy effects
BELL, R. Iris; KOITHAN Mary and J. BOOKS
Audrey (HOM. 102, 1/2013)
Key concepts of the Nanoparticle-Allostatic Cross-
Adaptation-Sensitization (NPCAS) Model for the
action of homœopathic remedies in living systems
include source nanoparticles as low level environmental
stressors, heterotypic hormesis, cross-adaptation,
allostasis (stress response network), time-dependent
sensitization with endogenous amplification and
bidirectional change, and self-organizing complex
adaptive systems. The model accommodates the
requirement for measurable physical agents in the
remedy (source nanoparticles and/or source absorbed to
silica nanoparticles). Hermetic adaptive responses in
the organism, triggered by nanoparticles; bipolar,
metaplastic change, dependent on the history of the
organism. Clinical matching of the patient’s symptom
picture, including modalities, to the symptom pattern
that the source material can cause (cross-adaptation and
cross-sensitization). Evidence for nanoparticle-related
quantum macro-entanglement in homœopathic
pathogenetic trials.
This paper examines research implications of the
model, discussing the following hypotheses: Variability
in nanoparticle size, morphology, and aggregation
affects remedy properties and reproducibility of
findings. Homœopathic remedies modulate adaptive
allostatic responses, with multiple dynamic short-and
long-term effects. Simillimum remedy nanoparticles, as
novel mild stressors corresponding to the organism’s
dysfunction initiate time-dependent cross-sensitization,
reversing the direction of dysfunctional reactivity to
environmental stressors.
The NPCAS model suggests a way forward for
systematic research on Homœopathy. The central
proposition is that homœopathic treatment is a form of
nanomedicine acting by modulation of endogenous
adaptation and metaplastic amplification processes in
the organism to enhance long-term, systemic resilience
and health.
10. Nanosized solvent superstructures in
ultramolecular aqueous dilutions: twenty years
research using water proton NMR relaxation
DEMANGEAT Jean-Louis (HOM. 102, 2/2013)
Background: Proton Nuclear Magnetic Resonance
(NMR) relaxation times T1, T12, T1/T2 are sensitive to
motion and organization of water molecules.
Especially, increase in T1/T2 reflects a higher degree of
structuring. My purpose was to look at physical
changes in water in ultrahigh aqueous dilutions.
Methods: Samples were prepared by iterative
centesimal (c) dilution with vigorous agitation, ranging
between 3c and 24c (Avogadro limit 12c). Solutes were
silica-lactose, histamine, manganese-lactose. Solvents
were water, NaCl 0.15 M or LiCl 0.15 M. Solvents
underwent strictly similar, simultaneous
dilution/agitation, for each level of dilution, as controls.
NMR relaxation was studied within 0.02-20 MHZ.
Results: No changes were observed in controls.
Increasing T1 and T1/T2 were found in dilutions, which
persisted beyond 9c (manganese-lactose), 10c
(histamine) and 12c (silica-lactose). For silica-lactose
in LiCl, continuous decrease in T2 with increase in
T1/T2 within the 12c-24c range indicated growing